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Therefore most vets recommend liquid Benadryl because a small amount is needed and you cant break a tablet into tiny pieces. For an average sized cat youll probably want to give half of a 25-milligram tablet. Because cats have altered liver metabolism called glucuronidation they metabolize acetaminophen poorly making them much more susceptible to poisoning.
A 10-pound cat will most likely need about four milliliters of liquid available at a concentration of 125mg5ml to get the right dose he says. So 16 lb cat x 5 8. The generally accepted dose is 1mg of Benadryl per pound of your cats body weight every 8-12 hours. Also liquid benadryl has a bad taste and cats usually hate it.
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